Spatial light interference microscopy: principle and applications to biomedicine
PDF Link In this paper, we review spatial light interference microscopy (SLIM), a common-path, phase-shifting interferometer, built onto a phase-contrast...
Multiscale Assay of Unlabeled Neurite Dynamics Using Phase Imaging with Computational Specificity
PDF Link Primary neuronal cultures have been widely used to study neuronal morphology, neurophysiology, neurodegenerative processes, and molecular mechanism of...
Computational interference microscopy enabled by deep learning
PDF Link Quantitative phase imaging (QPI) has been widely applied in characterizing cells and tissues. Spatial light interference microscopy (SLIM)...
Matrix Softness-Mediated 3D Zebrafish Hepatocyte Modulates Response to Endocrine Disrupting Chemicals
PDF Link Endocrine disrupting chemicals (EDC) include synthetic compounds that mimic the structure or function of natural hormones. While most...
High-resolution impedance mapping using electrically activated quantitative phase imaging
PDF Link Retrieving electrical impedance maps at the nanoscale rapidly via nondestructive inspection with a high signal-to-noise ratio is an...
Phase imaging with computational specificity (PICS) for measuring dry mass changes in sub-cellular compartments
PDF Link Due to its specificity, fluorescence microscopy has become a quintessential imaging tool in cell biology. However, photobleaching, phototoxicity,...
Quantifying myelin content in brain tissue using color Spatial Light Interference Microscopy (cSLIM)
PDF Link Deficient myelination of the brain is associated with neurodevelopmental delays, particularly in high-risk infants, such as those born...
Real-time Jones phase microscopy for studying transparent and birefringent specimens
PDF Link Tissue birefringence is an intrinsic marker of potential value for cancer diagnosis. Traditionally, birefringence properties have been studied...
Electrothermal soft manipulator enabling safe transport and handling of thin cell/tissue sheets and bioelectronic devices
PDF Link “Living” cell sheets or bioelectronic chips have great potentials to improve the quality of diagnostics and therapies. However,...
Network science characteristics of brain-derived neuronal cultures deciphered from quantitative phase imaging data
PDF Link Understanding the mechanisms by which neurons create or suppress connections to enable communication in brain-derived neuronal cultures can...