Cancer Detection

Posted on September 30, 2011 by admin

At the bottom of all optical methods for cancer imaging is the premise that the optical properties of tissues are affected by the disease. However, these cancer-induced changes have not been quantified directly. We are applying spatial light interference microscopy (SLIM) to quantitative-phase-image label-free biopsies as taken commonly from the patients. The intrinsic information provided by the refractive index distribution in tissues report on cancer onset and development without the need for staining. Currently, staining accounts for approximately 80% of the cost and preparation time of a biopsy. SLIM will provide a quantitative measure of cancer-induced optical changes in tissues and offer a faster, more accurate means for diagnosis. In the long run, SLIM may set the basis for novel in-vivo methods of cancer detection.