Archive: October, 2015

Plane-wave decomposition of spatially random fields

Posted on 10/12/15 by Tan Nguyen

PDF Link We investigate the uniqueness of the plane-wave decomposition of temporally deterministic, spatially random fields. Specifically, we consider the decomposition of spatially ergodic and, thus, statistically homogeneous fields. We show that when the spatial power spectrum is injective, the plane waves are the only possible coherent modes. Furthermore, the randomness of such fields originates […]

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Quantitative phase imaging of arthropods

Posted on 10/12/15 by Tan Nguyen

PDF Link Classification of arthropods is performed by characterization of fine features such as setae and cuticles. An unstained whole arthropod specimen mounted on a slide can be preserved for many decades, but is difficult to study since current methods require sample manipulation or tedious image processing. Spatial light interference microscopy (SLIM) is a quantitative […]

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Breast cancer diagnosis using spatial light interference microscopy

Posted on 10/12/15 by Tan Nguyen

PDF Link The standard practice in histopathology of breast cancers is to examine a hematoxylin and eosin (H&E) stained tissue biopsy under a microscope to diagnose whether a lesion is benign or malignant. This determination is made based on a manual, qualitative inspection, making it subject to investigator bias and resulting in low throughput. Hence, […]

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Measuring the Nonuniform Evaporation Dynamics of Sprayed Sessile Microdroplets with Quantitative Phase Imaging

Posted on 10/12/15 by Tan Nguyen

PDF Link We demonstrate real-time quantitative phase imaging as a new optical approach for measuring the evaporation dynamics of sessile microdroplets. Quantitative phase images of various droplets were captured during evaporation. The images enabled us to generate time-resolved three-dimensional topographic profiles of droplet shape with nanometer accuracy and, without any assumptions about droplet geometry, to […]

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Active intracellular transport in metastatic cells studied by spatial light interference microscopy

Posted on 10/12/15 by Tan Nguyen

PDF Link Spatiotemporal patterns of intracellular transport are very difficult to quantify and, consequently, con- tinue to be insufficiently understood. While it is well documented that mass trafficking inside living cells consists of both random and deterministic motions, quantitative data over broad spatiotemporal scales are lacking. We studied the intracellular transport in live cells using […]

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